Thursday Night Football tonight, September 17, is the Detroit Lions at the Buffalo Bills at 8:15 p.m. ET on Prime Video. It is the Week 2 Thursday game and the first regular season game at the new Highmark Stadium in Orchard Park. Both teams are 1-0 and Buffalo is favored by 4.5 to 5.5.
Tonight’s Game
| Matchup | Detroit Lions (1-0) at Buffalo Bills (1-0) |
| Kickoff | 8:15 p.m. ET / 5:15 p.m. PT |
| TV / stream | Prime Video nationally; local broadcast TV in Detroit and Buffalo; NFL+ on mobile |
| Pregame | TNF Tonight at 7 p.m. ET on Prime Video |
| Announcers | Al Michaels, Kirk Herbstreit, Kaylee Hartung |
| Odds | Bills -5.5, total 54.5 |
| Stadium | Highmark Stadium, Orchard Park, New York |
Upcoming Thursday Night Football Schedule
| Week | Date | Game |
|---|---|---|
| 2 | Sept. 17 | Lions at Bills |
| 3 | Sept. 24 | Falcons at Packers |
| 4 | Oct. 1 | Steelers at Browns |
| 5 | Oct. 8 | Buccaneers at Cowboys |
| 6 | Oct. 15 | Seahawks at Broncos |
| 7 | Oct. 22 | Patriots at Bears |
| 8 | Oct. 29 | Panthers at Packers |
| 9 | Nov. 5 | Jaguars at Ravens |
Every game kicks off at 8:15 p.m. ET on Prime Video. Week 1 had no Prime Video game; the season opened with a Wednesday night game and the traditional Thursday opener on NBC.
How to Watch Thursday Night Football
Prime Video is included with an Amazon Prime membership and is the only national home for the Thursday package. If you live in one of the two teams’ home markets, the game also airs on a local broadcast station, which is the free option. NFL+ carries the game on phones and tablets. See what channel Thursday Night Football is on for the full breakdown.
Related
Lions vs. Bills how to watch · Odds · Injury report · NFL games today
The Bottom Line
Tonight is Lions at Bills, 8:15 p.m. ET on Prime Video. Next Thursday it is Falcons at Packers.