Is James Cook playing this week? The live box below shows his current status from the Bills’ latest injury report, and the card under it shows the Bills’ next game, kickoff time and TV channel. Both update automatically as teams file their reports, so this page always reflects the latest official information.
The Bills play Sunday at 1:00 p.m. ET, October 4, hosting the Patriots.
| Kickoff | 1:00 p.m. ET / 10:00 a.m. PT |
| Date | Sunday, October 4, 2026 |
| Opponent | Patriots, at home |
| Stadium | Highmark Stadium |
Last time out: beat the Chargers 24 to 16 at home.
How NFL Injury Designations Work
Teams file practice reports during the week and give final game designations two days before kickoff. Out means the player will not play. Doubtful means he is unlikely to play. Questionable means his status is uncertain. A player with no designation is expected to play. Official inactive lists come out 90 minutes before kickoff, and players on injured reserve must miss at least four games.
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James Cook stats · Bills score · Bills injury report · What time do the Bills play · NFL injury report