NFL Week 1 Odds: Spreads and Betting Lines for Every Sunday Game

NFL WEEK 1 · SUNDAY, SEPTEMBER 13 · ALL TIMES ETTwelve of the 14 remaining games are 3.5 points or less
Time Game Spread Moneyline Total
1:00 Falcons at Steelers Steelers -3.5 ATL +155 / PIT -185 41.5
1:00 Ravens at Colts Ravens -3.5 BAL -180 / IND +150 48.5
1:00 Bills at Texans Bills -1.5 BUF -115 / HOU -105 44.5 to 45
1:00 Bears at Panthers Bears -2.5 to -3 CHI -155 / CAR +130 46.5
1:00 Browns at Jaguars Jaguars -8.5 CLE +325 / JAX -425 40.5
1:00 Saints at Lions Lions -6.5 NO +250 / DET -310 49.5
1:00 Jets at Titans Titans -1.5 NYJ +105 / TEN -125 39.5
1:00 Buccaneers at Bengals Bengals -3.5 TB +165 / CIN -200 50.5
4:25 Cardinals at Chargers Chargers -9.5 ARI +400 / LAC -550 47.5
4:25 Packers at Vikings Vikings -1.5 GB +100 / MIN -120 46.5
4:25 Dolphins at Raiders Raiders -3.5 MIA +155 / LV -185 40.5
4:25 Commanders at Eagles Eagles -5.5 WAS +190 / PHI -230 44.5
8:20 Cowboys at Giants (SNF) Cowboys -2.5 to -3 DAL -155 / NYG +130 48.5
Mon 8:15 Broncos at Chiefs (MNF) Chiefs -2.5 DEN +125 / KC -150 43.5

Lines are consensus numbers from bet365 (via Sportsbook Review, September 10) with Friday movement from BetMGM and DraftKings noted as ranges. They move all weekend; check your book before betting.

Already Played

Wednesday: Seahawks 13, Patriots 10. Seattle closed -3.5 and did not cover; the game went under 44.5. Thursday in Melbourne: the 49ers beat the Rams, who closed as 3.5 point favorites.

What Moved This Week

Bills at Texans opened Buffalo -1.5 in May, crossed to Houston -1 at times over the summer and settled back at Bills -1.5 with roughly 70 percent of the money on Buffalo. The total ticked from 44.5 to 45 at BetMGM. Bears at Panthers moved from -2.5 to -3 at DraftKings with more than 80 percent of tickets on Chicago. Falcons at Steelers is the one to watch after Tua Tagovailoa was ruled out Friday and Cooper Rush was named the starter; Pittsburgh sat at -3.5 before that news. Cowboys at Giants has hovered between Dallas -2.5 and -3 depending on the book.

Biggest and Smallest Numbers

The Chargers are the week’s largest favorite at -9.5 over Arizona and Jacoby Brissett, with Jacksonville -8.5 over Cleveland next. The Buccaneers at Bengals total of 50.5 is the highest on the board; Jets at Titans (39.5) is the lowest. Four games sit at 1.5 or less: Bills and Texans, Jets and Titans, Packers and Vikings, and effectively Bears and Panthers at the key number of 3.

Related: Week 1 injury report, Week 1 starting quarterbacks, Week 1 announcers, Super Bowl odds, NFL MVP odds.

The Bottom Line

Chargers -9.5 and Jaguars -8.5 are the only comfortable favorites on Sunday. Everything else is within a touchdown, and 12 of the 14 remaining Week 1 games are 3.5 points or less.