LSU vs. Ole Miss Odds: Spread, Over/Under, Moneyline and Line Movement for Saturday Night

NO. 7 LSU AT NO. 8 OLE MISS · SATURDAY, SEPTEMBER 19 · 7:30 P.M. ET, ABCLSU -2.5, total 58.5
Market LSU Ole Miss
Spread -2.5 +2.5
Moneyline (approx.) -140 +120
Total 58.5 (some books 57.5)
Opening line (FanDuel, Sept. 13) LSU -2.5, total 58.5
Summer lookahead (August) Ole Miss -2.5

LSU is the road favorite by a field goal or less at most books entering the weekend, and the number has held around 2.5 since it opened Sunday. Some books briefly went to LSU -3 or -3.5 midweek before the Tigers’ quarterback situation pulled it back under the key number of three. The total sits at 58.5 at most shops, with 57.5 available.

What Moved the Line

The market’s biggest question is whether Sam Leavitt plays. LSU listed its starting quarterback as doubtful on Wednesday’s SEC availability report with a throwing shoulder issue, then upgraded him to questionable on Thursday. Books shaded the line toward Ole Miss after the first report and drifted back after the upgrade. Leading tackler TJ Dottery is also questionable. Ole Miss staffers told ESPN they are not convinced the designation is sincere, and the SEC’s policy carries fines of up to $100,000 for gamesmanship on availability reports. The full picture is on our LSU vs. Ole Miss injury report.

The August lookahead had Ole Miss favored by 2.5, so the market has swung about five points toward LSU since summer, almost entirely because of the Tigers’ defense: 140 net yards allowed and seven sacks against Louisiana Tech, 10 points allowed to Clemson.

Trends Worth Knowing

  • The home team has won the last six meetings in this series.
  • Ole Miss has scored exactly 41 points in both games (41-38 over Louisville, 41-9 over Charlotte). LSU has scored 51 and 45.
  • Leavitt has four interceptions in two games, three of them in the first half against Louisiana Tech. Trinidad Chambliss went 23 of 26 for Ole Miss last week.
  • Kewan Lacy returned from a thigh bruise to run for 87 yards and two scores last week.

How to Watch

Kickoff is 7:30 p.m. ET on ABC with Chris Fowler and Kirk Herbstreit. College GameDay is live from The Grove at 9 a.m. ET on ESPN. Full details on the LSU vs. Ole Miss matchup page, the forecast on the weather page, and the live score on the score page. Odds are for informational purposes and change often; check your book before betting.