Live betting odds for the Los Angeles Chargers at the Buffalo Bills, Sunday, September 27, at 1 p.m. ET. The spread, moneyline and total below compare prices across sportsbooks and prediction markets and update automatically until kickoff.
Chargers +8.5 | total 40.5
| Sportsbook | Chargers spread | Bills spread | Total | Chargers ML | Bills ML |
|---|
| DraftKings | +8.5 (-1300) | -8.5 (+790) | 40.5 (+620) | +4600 | -10000 |
| Caesars | +8.5 (-800) | -8.5 (+450) | 37.5 (-213) | +3000 | -10000 |
| Polymarket | +1.5 (+22122) | -1.5 (-22122) | 54.5 (+19900) | +199900 | -199900 |
| Kalshi | -1.5 (+4900) | +1.5 (-4900) | 71.5 (+9900) | +9900 | -19900 |
| FanDuel | +7.5 (+1280) | -7.5 (-7000) | 40.5 (+850) | +5500 | -100000 |
| BetRivers | +7.5 (+195) | -7.5 (-265) | 36.5 (-175) | +800 | -1667 |
| BetMGM | +11.5 (+170) | -11.5 (-235) | 41.5 (+190) | +3300 | -25000 |
| Fanatics | +7.5 (+1500) | -7.5 (-8000) | 40.5 (+1500) | +12000 | -100000 |
Lines from BALLDONTLIE and refreshed automatically. Numbers move, so confirm at your sportsbook before betting.
Chargers vs. Bills Player Props
DJ Moore WR BUF
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +10000 Fanatics | | 2 |
Dalton Kincaid TE BUF
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +10000 Fanatics | | 3 |
Dawson Knox TE BUF
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +10000 Fanatics | | 3 |
Greg Dortch WR BUF
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +5000 BetRivers | | 1 |
Jackson Hawes TE BUF
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +10000 Fanatics | | 3 |
James Cook III RB BUF
| Prop | Line | Best over | Best under | Books |
|---|
| Rushing yards | 122.5 | -121 BetRivers | -125 BetRivers | 1 |
| Anytime TD | Yes | +8000 BetMGM | | 3 |
Josh Allen QB BUF
| Prop | Line | Best over | Best under | Books |
|---|
| Passing yards | 201.5 | -114 Caesars | -114 Caesars | 1 |
| Rushing yards | 20.5 | -114 BetRivers | -132 BetRivers | 1 |
| Anytime TD | Yes | +6000 Fanatics | | 3 |
Joshua Palmer WR BUF
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +10000 Fanatics | | 2 |
Keleki Latu TE BUF
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +10000 Fanatics | | 2 |
Keon Coleman WR BUF
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +2400 BetRivers | | 1 |
Khalil Shakir WR BUF
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +10000 Fanatics | | 2 |
Ray Davis RB BUF
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +10000 Fanatics | | 3 |
Ty Johnson RB BUF
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +10000 Fanatics | | 3 |
Alec Ingold FB LAC
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +6000 Fanatics | | 3 |
Derius Davis WR LAC
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +3500 BetMGM | | 3 |
Hayden Rucci TE LAC
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +4000 Fanatics | | 3 |
Justin Herbert QB LAC
| Prop | Line | Best over | Best under | Books |
|---|
| Passing yards | 195.5 | -114 Caesars | -114 Caesars | 1 |
| Passing TDs | 1.5 | +275 BetMGM | -286 BetRivers | 3 |
| Anytime TD | Yes | +2500 Fanatics | | 3 |
Keaton Mitchell RB LAC
| Prop | Line | Best over | Best under | Books |
|---|
| Rushing yards | 52.5 | -113 BetRivers | -134 BetRivers | 1 |
| Anytime TD | Yes | +3000 Fanatics | | 3 |
Kimani Vidal RB LAC
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +5000 Fanatics | | 3 |
Ladd McConkey WR LAC
| Prop | Line | Best over | Best under | Books |
|---|
| Receiving yards | 43.5 | -124 BetRivers | -115 BetRivers | 1 |
| Anytime TD | Yes | +1050 BetMGM | | 3 |
Marquez Valdes-Scantling WR LAC
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +3300 BetMGM | | 2 |
Omarion Hampton RB LAC
| Prop | Line | Best over | Best under | Books |
|---|
| Receiving yards | 10.5 | +550 Fanatics | -1200 Fanatics | 1 |
| Anytime TD | Yes | +1300 Fanatics | | 3 |
Oronde Gadsden TE LAC
| Prop | Line | Best over | Best under | Books |
|---|
| Receiving yards | 1.5 | +125 BetMGM | -165 BetMGM | 1 |
| Anytime TD | Yes | +1800 Caesars | | 4 |
Patrick Herbert TE LAC
| Prop | Line | Best over | Best under | Books |
|---|
| Anytime TD | Yes | +3500 BetRivers | | 2 |
Quentin Johnston WR LAC
| Prop | Line | Best over | Best under | Books |
|---|
| Receiving yards | 40.5 | +125 BetMGM | -165 BetMGM | 1 |
| Anytime TD | Yes | +1300 BetMGM | | 3 |
Tre' Harris WR LAC
| Prop | Line | Best over | Best under | Books |
|---|
| Receiving yards | 50.5 | +145 BetMGM | -200 BetMGM | 1 |
| Anytime TD | Yes | +1700 Fanatics | | 3 |
Player props from BALLDONTLIE, refreshed every 10 minutes. Each line is the most common one across sportsbooks, with the best over and under price at that line. Anytime TD shows the best price to score. Lines move; check your sportsbook before betting. Must be 21 or older where legal. Gambling problem? Call 1-800-GAMBLER.
Reading the Lines
A negative spread marks the favorite and a positive spread the underdog. Moneylines show what a $100 bet returns on the underdog, or what it takes to win $100 on the favorite. The total is the combined points for both teams, with bets on the over or under. Prediction markets such as Kalshi and Polymarket appear alongside traditional sportsbooks, and their prices will not always match.
Must be 21 or older where legal. Gambling problem? Call 1-800-GAMBLER.
More Chargers vs. Bills
Chargers vs. Bills preview · Chargers score · Bills score · All Week 3 odds · NFL player props today
