Quarterbacks
| Pos | Starter | 2nd | 3rd |
|---|
| QB | Justin Herbert | Trey Lance | |
Running Backs
| Pos | Starter | 2nd | 3rd |
|---|
| FB | Alec Ingold | Scott Matlock Injured reserve | |
| RB | Omarion Hampton | Keaton Mitchell | Kimani Vidal |
Wide Receivers
| Pos | Starter | 2nd | 3rd |
|---|
| WR | Ladd McConkey | Brenen Thompson | KeAndre Lambert-Smith Injured reserve |
Tight Ends
| Pos | Starter | 2nd | 3rd |
|---|
| TE | Oronde Gadsden | Charlie Kolar Out | David Njoku Out |
Offensive Line
| Pos | Starter | 2nd | 3rd |
|---|
| C | Jake Slaughter | Jacob Spomer | Tyler Biadasz Injured reserve |
| LG | Kayode Awosika Questionable | Trey Pipkins III Out | Alex Harkey |
| LT | Rashawn Slater | Trey Pipkins III Out | Logan Taylor |
| RG | Cole Strange | Trevor Penning | |
| RT | Joe Alt | Travis Burke | |
Defensive Line
| Pos | Starter | 2nd | 3rd |
|---|
| LDE | Teair Tart | Nick Barrett | |
| NT | Dalvin Tomlinson Questionable | | |
| RDE | Jamaree Caldwell | Justin Eboigbe | |
Linebackers
| Pos | Starter | 2nd | 3rd |
|---|
| LILB | Daiyan Henley | Marlowe Wax | |
| RILB | Del'Shawn Phillips | Troy Dye | Denzel Perryman Injured reserve |
| SLB | Khalil Mack | Akheem Mesidor | |
| WLB | Tuli Tuipulotu | Bud Dupree | |
Defensive Backs
| Pos | Starter | 2nd | 3rd |
|---|
| FS | Elijah Molden Out | Genesis Smith | RJ Mickens |
| LCB | Cam Hart | Rodney Shelley | |
| NB | Tarheeb Still | | |
| RCB | Donte Jackson | Deane Leonard Out | Isas Waxter |
| SS | Derwin James Jr. Questionable | Tony Jefferson | Kendall Williamson |
Special Teams
| Pos | Starter | 2nd | 3rd |
|---|
| H | JK Scott | | |
| KR | Derius Davis | Keaton Mitchell | Kimani Vidal |
| LS | Josh Harris | | |
| P | JK Scott | | |
| PK | Cameron Dicker | | |
| PR | Derius Davis | Brenen Thompson | KeAndre Lambert-Smith Injured reserve |
Other
| Pos | Starter | 2nd | 3rd |
|---|
| WR-2 | Quentin Johnston | Derius Davis | |
| WR-3 | Tre' Harris | Gary Jennings | |
Roster and depth chart from BALLDONTLIE, refreshed every six hours.
About This Depth Chart
Starters are listed first, then the second and third string at each position. Injury designations appear next to affected players, and the chart updates on its own as the team adjusts its lineup through the season.
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