Lions at Bills on Thursday, September 17 (8:15 p.m. ET, Prime Video) has a 53.5 point total and two of the highest scoring offenses in the league, so the prop board is deep. The headline lines: Josh Allen 250.5 passing yards and 30.5 rushing yards, Jared Goff 270.5 passing yards, Jahmyr Gibbs 90.5 rushing yards, James Cook 75.5 rushing yards and Amon-Ra St. Brown 7.5 receptions. Lines are from the major books as of Wednesday and move before kickoff.
Quarterback Props
| Player | Prop | Line | Week 1 |
|---|---|---|---|
| Josh Allen (BUF) | Passing yards | 250.5 | 334 at Houston |
| Josh Allen (BUF) | Rushing yards | 30.5 | 2 rushing TD at Houston |
| Jared Goff (DET) | Passing yards | 270.5 | 206 (26 of 39) vs. New Orleans |
Allen’s passing line sits well under his Week 1 total against what had been the best defense in the league by EPA last season, and he did it with two 100 yard receivers. Detroit is without both starting safeties, Brian Branch and Kerby Joseph, which is why most public analysis leans to the over. Goff’s number is set higher than Allen’s even though Goff threw for 206 in Week 1; the book is pricing a game where Detroit has to throw to keep up, and Goff threw for 494 the last time these teams met in 2024.
Running Back Props
| Player | Prop | Line | Week 1 |
|---|---|---|---|
| Jahmyr Gibbs (DET) | Rushing yards | 90.5 | 156 on 29 carries, 2 TD |
| Jahmyr Gibbs (DET) | Receiving yards | Around 30 to 35 | 5 catches, 30 yards |
| James Cook (BUF) | Rushing yards | 75.5 | Buffalo held Houston’s backs to 60 on 20 carries |
Gibbs touched the ball 34 times in Week 1 and played 74 percent of the snaps as the clear lead back with Isiah Pacheco on injured reserve. Bills defensive coordinator Jim Leonhard said stopping Gibbs is Buffalo’s first priority because Detroit’s play action and bootleg game all runs through him. The receiving line is the softer number: Buffalo allowed 114 yards after the catch in Week 1 and Gibbs is Goff’s checkdown when the pass rush gets home. Cook, last year’s rushing champion, shares red zone work with Allen, which is the usual warning on his touchdown props.
Receiver and Tight End Props
| Player | Prop | Line | Week 1 |
|---|---|---|---|
| Amon-Ra St. Brown (DET) | Receptions | 7.5 | 10 catches on 14 targets, 2 TD |
| Amon-Ra St. Brown (DET) | Anytime TD | +110 | 2 TD |
| DJ Moore (BUF) | Receiving yards | Check book | 5 catches, 100 yards |
| Dalton Kincaid (BUF) | Receiving yards | Check book | 130 yards |
St. Brown played nearly 90 percent of Detroit’s snaps and drew 14 targets; 7.5 receptions is priced near even money and is the most popular over on the board. Moore and Kincaid each went over 100 against Houston, so their yardage lines opened higher than usual for a Bills pass catcher.
Anytime Touchdown Prices
Gibbs is the heaviest favorite on the board at roughly -300 or shorter at most books. St. Brown is around +110, and Cook and Allen are priced as favorites to score given Buffalo’s red zone split. Exact numbers vary by book and are worth shopping; prediction markets have offered better prices than sportsbooks on Gibbs this week.
Related
Lions vs. Bills odds · Same game parlay · Injury report · Starting lineups · DFS showdown
The Bottom Line
Allen 250.5 passing, Goff 270.5, Gibbs 90.5 rushing, Cook 75.5, St. Brown 7.5 catches. The Week 1 box scores blew through most of these numbers, which is why the totals and the overs are drawing the money. Updated lines are posted here before kickoff.