The Lions game tonight kicks off at 8:15 p.m. ET on Thursday, September 17. Detroit is at Buffalo for Thursday Night Football, the first regular season game at the new Highmark Stadium, and it streams on Prime Video. In the Detroit and Buffalo markets the game also airs on a local over the air station, so fans in Michigan and Western New York do not need Prime to watch.
Kickoff Time by Time Zone
| Eastern | 8:15 p.m. |
| Central | 7:15 p.m. |
| Mountain | 6:15 p.m. |
| Arizona | 5:15 p.m. |
| Pacific | 5:15 p.m. |
| Alaska | 4:15 p.m. |
| Hawaii | 2:15 p.m. |
| UK | 1:15 a.m. Friday |
TNF Tonight, the pregame show, starts at 7 p.m. ET on Prime Video.
How to Watch the Lions Tonight
| Streaming (national) | Prime Video, included with Amazon Prime |
| Local TV | WJBK FOX 2 in Detroit; WKBW Channel 7 in Buffalo |
| Phone and tablet | NFL+ (mobile only) |
| Radio | WXYT 97.1 The Ticket (Dan Miller, Lomas Brown), Westwood One nationally |
| Announcers | Al Michaels, Kirk Herbstreit, Kaylee Hartung |
Odds and Injuries
Buffalo is a 4.5 point favorite at most books, with a total of 53.5 and a Lions moneyline around +185. Detroit is missing left guard Christian Mahogany and right tackle Blake Miller, and cornerback D.J. Reed is questionable with a foot injury. Larry Borom starts at right tackle and Ben Bartch at left guard. Full details on the injury report and odds pages.
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The Bottom Line
Lions at Bills, 8:15 p.m. ET tonight on Prime Video, plus local broadcast TV in Detroit. After tonight the Lions get the long Thursday to Sunday layoff before Week 3.