Thursday Night Football tonight kicks off at 8:15 p.m. ET. The Detroit Lions visit the Buffalo Bills at the new Highmark Stadium on Thursday, September 17, the first Prime Video game of the 2026 season. The pregame show, TNF Tonight, starts at 7 p.m. ET.
Kickoff Time by Time Zone
| Time zone | Pregame | Kickoff |
|---|---|---|
| Eastern | 7:00 p.m. | 8:15 p.m. |
| Central | 6:00 p.m. | 7:15 p.m. |
| Mountain | 5:00 p.m. | 6:15 p.m. |
| Arizona | 4:00 p.m. | 5:15 p.m. |
| Pacific | 4:00 p.m. | 5:15 p.m. |
| Alaska | 3:00 p.m. | 4:15 p.m. |
| Hawaii | 1:00 p.m. | 2:15 p.m. |
How to Watch
Prime Video carries every Thursday night game in 2026 and is included with an Amazon Prime membership. Fans in the Detroit and Buffalo markets can also watch on a local over the air station, and NFL+ has the game on phones and tablets. Al Michaels calls the game with Kirk Herbstreit and Kaylee Hartung; Charissa Thompson hosts the studio show with Tony Gonzalez, Ryan Fitzpatrick, Andrew Whitworth and Richard Sherman. More on the what channel is TNF on page.
Tonight’s Game
Buffalo is a 4.5 point favorite with a 53.5 total in a matchup of two 1-0 teams that scored 36 and 31 points in Week 1. Josh Allen threw for 334 yards and accounted for four touchdowns at Houston; Jahmyr Gibbs ran for 156 and two scores against New Orleans. The Lions are down two starting offensive linemen, and cornerback D.J. Reed is questionable. It is also the first regular season game at Buffalo’s new $2.2 billion stadium.
Next Week’s Thursday Night Football
Week 3 Thursday Night Football is Thursday, September 24 at 8:15 p.m. ET on Prime Video. The matchup is on our who plays Thursday night football page, which updates each week.
Related
Lions vs. Bills preview · Odds · Injury report · Announcers · Live score
The Bottom Line
Thursday Night Football tonight is Lions at Bills, 8:15 p.m. ET, 5:15 p.m. PT, on Prime Video, with the pregame show at 7 p.m. ET.