Patriots vs. Bills: Game Time, TV Channel and Matchup Guide

The New England Patriots visit the Buffalo Bills on Sunday, October 4, at 1:00 p.m. ET at Highmark Stadium, on CBS or FOX depending on your market. Below are the kickoff details, both teams’ live injury reports, the current betting lines and player props, all updating automatically through kickoff.

Date Sunday, October 4, 2026
Kickoff 1:00 p.m. ET, 12:00 p.m. CT
TV CBS or FOX, regional
Stadium Highmark Stadium, Orchard Park, New York

Live Injury Report

New England Patriots

PlayerPosStatusLatestUpdated
A.J. BrownWRIRBrown was spotted Monday in the Patriots' locker room walking without a limp and wearing a small wrap on his injured right ankle, Taylor Kyles of CLNSMedia.com reports.Sep 28
Quintayvious HutchinsLBIRHutchins (knee) was placed on injured reserve Friday.Sep 25
Dell PettusSIRThe Patriots placed Pettus (ankle) on injured reserve Wednesday.Sep 23
Mike OnwenuGIRThe Patriots placed Onwenu (ankle) on injured reserve Tuesday.Sep 22
Bryce BaringerPIRThe Patriots placed Baringer (undisclosed) on injured reserve Monday.Sep 1
Khalil JacobsLBIRThe Patriots placed Jacobs (undisclosed) on injured reserve Monday.Sep 1
Marcus BryantOTIR-RThe Patriots placed Bryant (ankle) on injured reserve with a designation to return Sunday.Aug 31
Myles MontgomeryRBIRAug 19
Jeremiah WebbWRIRArm
Julian HillTEIRKnee
Brenden SchoolerSNFI-RThe Patriots opened the 21-day practice window for Schooler (back) on Wednesday.Sep 23
Harold Landry IIILBPUP-RLandry (undisclosed) was moved to the reserve/PUP list by the Patriots on Sunday.Aug 31

Listed for the previous game and not yet on this week's report: Ben Brown (questionable), TreVeyon Henderson (questionable), Efton Chism III (inactive), Erick Hunter (inactive), Behren Morton (inactive), Karon Prunty (inactive), Walter Rouse (inactive), Dametrious Crownover (inactive), Carlton Davis III (questionable), Dre'Mont Jones (questionable), Robert Spillane (questionable), Tanner Arkin (inactive), Leonard Taylor III (inactive), Eli Raridon (questionable), Craig Woodson (questionable), Reggie Gilliam (questionable), Morgan Moses (questionable), Christian Barmore (questionable), Greg Van Roten (questionable).

Buffalo Bills

PlayerPosStatusLatestUpdated
Jordan HancockCBIRThe Bills placed Hancock (hamstring) on injured reserve Friday.Sep 25
Zane DurantDTIR-RSep 8
Tyrell ShaversWRPUP-RSep 8
Dorian StrongCBNFI-RSep 8
Phidarian MathisDTReserve-Susreserve-susAug 19

Listed for the previous game and not yet on this week's report: Ty Johnson (questionable), T.J. Sanders (doubtful), Skyler Bell (inactive), Jude Bowry (inactive), Mike Danna (inactive), Jalon Kilgore (inactive), Ar'maj Reed-Adams (questionable), Terrel Bernard (questionable), Cole Bishop (questionable), Ed Oliver (questionable), DJ Moore (questionable), Keon Coleman (questionable), Christian Benford (questionable), Josh Allen (questionable).

Injury data from BALLDONTLIE, refreshed every 30 minutes. Last checked Sep 29, 9:49 am ET.

Current Odds

Patriots +7 | total 48.5

SportsbookPatriots spreadBills spreadTotalPatriots MLBills ML
DraftKings+7 (-115)-7 (-105)48.5 (-110)+240-298
Caesars+6.5 (-104)-6.5 (-117)48.5 (-110)+250-320
Polymarket+6.5 (+106)-6.5 (-106)47.5 (-113)+264-264
Kalshi+6.5 (+111)-6.5 (-111)48.5 (+106)+264-277
FanDuel+6.5 (-104)-6.5 (-118)48.5 (-110)+265-330
BetRivers+7 (-118)-7 (-103)48.5 (-109)+250-315
BetMGM+6.5 (-102)-6.5 (-118)48.5 (-108)+270-325
Fanatics+6.5 (-105)-6.5 (-115)48.5 (-105)+250-320

Lines from BALLDONTLIE and refreshed automatically. Numbers move, so confirm at your sportsbook before betting.

Player Props

DJ Moore WR BUF

PropLineBest overBest underBooks
Anytime TDYes+175 BetMGM5

Dalton Kincaid TE BUF

PropLineBest overBest underBooks
Anytime TDYes+175 DraftKings5

Dawson Knox TE BUF

PropLineBest overBest underBooks
Anytime TDYes+700 FanDuel5

Greg Dortch WR BUF

PropLineBest overBest underBooks
Anytime TDYes+2800 BetMGM3

Jackson Hawes TE BUF

PropLineBest overBest underBooks
Anytime TDYes+1550 BetMGM3

James Cook III RB BUF

PropLineBest overBest underBooks
Anytime TDYes-145 BetMGM5

Josh Allen QB BUF

PropLineBest overBest underBooks
Passing yards238.5-112 DraftKings-112 DraftKings1
Passing TDs1.5-148 DraftKings+116 DraftKings2
Anytime TDYes-115 Fanatics5

Joshua Palmer WR BUF

PropLineBest overBest underBooks
Anytime TDYes+600 BetMGM5

Keleki Latu TE BUF

PropLineBest overBest underBooks
Anytime TDYes+2500 BetMGM3

Keon Coleman WR BUF

PropLineBest overBest underBooks
Anytime TDYes+450 Fanatics5

Khalil Shakir WR BUF

PropLineBest overBest underBooks
Anytime TDYes+230 BetMGM5

Ray Davis RB BUF

PropLineBest overBest underBooks
Anytime TDYes+1050 BetMGM3

Skyler Bell WR BUF

PropLineBest overBest underBooks
Anytime TDYes+2000 Fanatics1

Ty Johnson RB BUF

PropLineBest overBest underBooks
Anytime TDYes+500 FanDuel4

Cameron Latu TE NE

PropLineBest overBest underBooks
Anytime TDYes+1550 BetMGM3

Corey Kiner RB NE

PropLineBest overBest underBooks
Anytime TDYes+2000 DraftKings5

DeMario Douglas WR NE

PropLineBest overBest underBooks
Anytime TDYes+390 DraftKings5

Drake Maye QB NE

PropLineBest overBest underBooks
Passing yards228.5-112 DraftKings-112 DraftKings1
Passing TDs1.5+136 FanDuel-154 DraftKings2
Anytime TDYes+490 FanDuel5

Efton Chism III WR NE

PropLineBest overBest underBooks
Anytime TDYes+1500 DraftKings5

Eli Raridon TE NE

PropLineBest overBest underBooks
Anytime TDYes+900 BetMGM3

Hunter Henry TE NE

PropLineBest overBest underBooks
Anytime TDYes+270 BetMGM5

Kyle Williams WR NE

PropLineBest overBest underBooks
Anytime TDYes+750 DraftKings5

Mack Hollins WR NE

PropLineBest overBest underBooks
Anytime TDYes+290 DraftKings5

Reggie Gilliam FB NE

PropLineBest overBest underBooks
Anytime TDYes+2500 BetMGM2

Rhamondre Stevenson RB NE

PropLineBest overBest underBooks
Anytime TDYes+150 Fanatics5

Romeo Doubs WR NE

PropLineBest overBest underBooks
Anytime TDYes+260 BetMGM5

Tanner Arkin TE NE

PropLineBest overBest underBooks
Anytime TDYes+1900 Fanatics1

TreVeyon Henderson RB NE

PropLineBest overBest underBooks
Anytime TDYes+190 Fanatics5

Player props from BALLDONTLIE, refreshed every 10 minutes. Each line is the most common one across sportsbooks, with the best over and under price at that line. Anytime TD shows the best price to score. Lines move; check your sportsbook before betting. Must be 21 or older where legal. Gambling problem? Call 1-800-GAMBLER.

Game Day Pages

Live score · Week 4 odds · Bills inactives · Patriots inactives · Bills injury report · Patriots injury report · AFC East standings