Louisville Football Schedule 2026: Full Cardinals Slate, Dates, and Key Games

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Louisville’s 2026 season opens on a Sunday night in Nashville. Jeff Brohm’s fourth Cardinals team faces Ole Miss at Nissan Stadium on Sept 6, then comes home for three straight at L&N Stadium — including a Friday night home opener against Villanova.

This schedule was rebuilt on the fly: the Georgia home-and-home was cancelled, Ole Miss was added in its place, and the Charlotte game was scrapped to make room for a ninth ACC game. Several schedule sites still show the old version, or list the opener on Saturday Sept 5.

2026 Team Schedule
Louisville Football Schedule
ACC · L&N Federal Credit Union Stadium · Jeff Brohm (4th year)
7
Home Games
9
ACC Games
Sun Sept 6
Opener vs Ole Miss
Oct 9
Circle It: Florida State
Date Opponent Time (ET) / TV Result
Sun, Sept 6 vs Ole Miss (Nashville) 7:30 PM —
Fri, Sept 11 vs Villanova (home opener) 7:00 PM —
Sat, Sept 19 vs SMU (ACC opener) 3:30 PM —
Sat, Sept 26 vs Wake Forest TBA —
Sat, Oct 3 at NC State TBA —
Fri, Oct 9 vs Florida State 7:00 PM —
Sat, Oct 17 at Syracuse TBA —
Sat, Oct 24 Bye Week — —
Sat, Oct 31 vs Stanford TBA —
Sat, Nov 7 at Georgia Tech TBA —
Sat, Nov 14 at North Carolina TBA —
Sat, Nov 21 vs Pittsburgh (home finale) TBA —
Sat, Nov 28 at Kentucky (Governor’s Cup) TBA —

Games That Will Decide Louisville’s Season

Sept 6 vs Ole Miss A Sunday night national window in Nashville against a top-10 SEC team. Ole Miss beat Louisville 43-24 in a 2021 neutral-site opener in Atlanta.
Sept 19 vs SMU Louisville still hasn’t beaten SMU since the Mustangs joined the ACC in 2024. The conference opener at home is the chance to fix that.
Oct 9 vs Florida State A Friday night at L&N Stadium, and the first meeting since the 2023 ACC Championship Game, which FSU won 16-6. The biggest home date of the year.
Nov 28 at Kentucky The Governor’s Cup in Lexington closes the year. Louisville won last season’s meeting 41-0, and now faces a Kentucky team under first-year coach Will Stein.
A Schedule Rebuilt Twice
Louisville and Georgia mutually cancelled their home-and-home, Ole Miss was added as a neutral-site opener, and the Charlotte game was scrapped to make room for a ninth ACC game.
Nine ACC Games, Early
The ACC goes to a nine-game conference schedule league-wide in 2027, but 12 teams — Louisville among them — start in 2026. Others stay at eight to honor prior commitments.
Stanford, for the First Time
The Oct 31 game is the first time Louisville has ever hosted Stanford — one of the stranger fixtures the ACC’s expanded footprint has produced.

How the Schedule Sets Up

Ole Miss is a free swing on a national stage, and then Louisville gets three straight at home to build momentum — Villanova on a Friday, SMU, Wake Forest. The road stretch that follows is where the season is decided: NC State, then Florida State at home on a Friday night, then Syracuse. The bye on Oct 24 sets up a November of Stanford at home, back-to-back road trips to Georgia Tech and North Carolina, Pitt for the home finale, and the Governor’s Cup in Lexington. Seven home games and no game against Clemson or Miami is a favorable ACC draw; eight or nine wins is a fair expectation. For the postseason picture, here’s how the College Football Playoff works under the 12-team format. The ACC’s move to nine league games reflects the NCAA FBS shift toward deeper conference scheduling.

The Bottom Line

A Sunday night opener in Nashville, seven home games, Florida State under the lights on a Friday, and the Governor’s Cup to close — Jeff Brohm’s fourth Louisville schedule dodges Clemson and Miami and gives the Cardinals a real path to a strong ACC finish. Bookmark this page; times, networks, and results are updated throughout the season.