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How Week 1 Opens
Wednesday, September 9: New England at Seattle, 8:20 p.m. ET. The league opener falls on a Wednesday this year, and the Seahawks are the modest home favorite.
Thursday, September 10: San Francisco at the Los Angeles Rams, 8:35 p.m. ET. A division game to open the week proper, and the Rams are both the home team and the Super Bowl market favorite.
Sunday, September 13: a ten game window. At 1 p.m. ET: Chicago at Carolina, Baltimore at Indianapolis, Atlanta at Pittsburgh, Cleveland at Jacksonville, Tampa Bay at Cincinnati, the Jets at Tennessee, New Orleans at Detroit and Buffalo at Houston, which the model has as the closest game of the week at almost exactly even. At 4:25: Arizona at the Chargers, Green Bay at Minnesota, Miami at Las Vegas and Washington at Philadelphia.
Sunday Night Football: Dallas at the New York Giants, 8:20 p.m. ET on NBC.
The Games That Matter Most
Buffalo at Houston is the one to watch: two playoff teams, a true toss up, and Josh Allen opening an MVP campaign as the co favorite on the board. Green Bay at Minnesota is the best division game. Dallas at the Giants gets the national window and will draw the biggest audience of the weekend regardless of what either team is. Every price is on NFL MVP odds and Super Bowl odds.
Related
What NFL games are on today · NFL playoff odds · AFC East · NFC East · Cowboys schedule · Chiefs schedule
The Bottom Line
NFL Week 1 runs Wednesday, September 9 through Sunday night, September 13, opening with New England at Seattle and closing with Dallas at the Giants. The table above fills in networks and results on its own.