Buffalo visits No. 14 Penn State on Saturday, September 19 at noon ET on Big Ten Network, a nonconference game at Beaver Stadium before the Nittany Lions turn to the Big Ten schedule.
Odds and Spread
Buffalo +42.5 | total 68.5
| Sportsbook | Buffalo spread | Penn State spread | Total | Buffalo ML | Penn State ML |
|---|---|---|---|---|---|
| FanDuel | 68.5 (+490) | ||||
| DraftKings | +42.5 (-10000) | -42.5 (+3100) | 68.5 (+3000) | ||
| BetMGM | +42.5 (-1200) | -42.5 (+825) | 68.5 (+650) | ||
| Fanatics | +42.5 (-3000) | -42.5 (+950) | 69.5 (+950) | ||
| Caesars | +42.5 (-1700) | -42.5 (+700) | 68.5 (+360) |
Lines from BALLDONTLIE and refreshed automatically. Numbers move, so confirm at your sportsbook before betting.
Penn State is a heavy home favorite, one of the wider numbers on the Week 3 board. With a spread this large the total and the first half line carry more information than the side does.
Start Time, TV Channel and How to Watch
| Date | Saturday, September 19, 2026 |
| Kickoff | 12:00 p.m. ET |
| TV | Big Ten Network |
| Streaming | Fox One and the FOX Sports app with a TV provider login that includes BTN, or Fubo, YouTube TV, Hulu + Live TV, DirecTV Stream and Sling Blue |
| Rankings | Penn State No. 14 in the AP Top 25, Buffalo unranked |
| Stadium | Beaver Stadium, University Park, Pennsylvania |
How Both Teams Got Here
Penn State is 2-0 with a 45-0 shutout of Marshall and a 27-9 win at Temple. The defense has allowed nine points in two games, which is the number that matters most here.
Buffalo is 1-1. The Bulls beat UAlbany 21-17 in a game they should have won more comfortably, then lost 33-20 at Florida International in Week 2.
What to Watch
Penn State’s defense against anyone at all. Nine points allowed across two games is elite on paper, but Marshall and Temple are not a reliable test. Buffalo will not provide one either, which means the Nittany Lions go into Big Ten play with a defensive profile nobody can properly evaluate.
For Buffalo, losing to FIU by 13 is the honest marker of where this team is. A noon kickoff at Beaver Stadium against a top 15 opponent is a guarantee game, and the realistic goal is keeping the starters on the field into the third quarter.
Related
Penn State football score · Big Ten standings · AP Top 25 · Big Ten scores · College football scores
The Bottom Line
Buffalo at No. 14 Penn State kicks off Saturday, September 19 at noon ET on Big Ten Network from Beaver Stadium. Penn State has allowed nine points in two games; Buffalo is coming off a loss at FIU. The odds table above updates automatically.